Anticancer agents(Antineopastic/Cytotoxic agents),Introduction, Type of Neoplasm or Cancer, Classification of Anticancer Agents, Pharmacodynamics of Anticancer agents, Pharmacokinetics of Anticancer agents,

Agents used for the treatment of cancer knows as anticancer agents.
Those agents which is useful in the treatment of abnormal proliferation of unwanted cell growth by abnormal cell division.
Note- Proliferation means Formation or Development of cell.
Cancer is an abnormal proliferation of unwanted cell growth which is a cellular in nature know to neoplasm or cancer.
Type of Neoplasm or Cancer-
Cancer is generally two types-
1.Benign type-This type of cancer don’t have Metastasis nature.
2.Malignant type-This type of cancer have Metastasis nature.
Note- vMetastasis-   it is a movement of neoplastic or cancer cell to a distant cell invaded them for abnormal proliferation.
vAdenoma and Fibroma is a Benign type of cancer having Glandular tissue and Connective tissue.
vCarcinoma and Sarcoma is a malignant type of cancer Glandular and Connective tissue.
vMyeloid- when leukocytes or WBC(white blood cells) is behaving like a cancer cell is known as myeloid.
Classification of …

Therapeutic Drug Monitoring (TDM), Aim of TDM, Introduction of TDM, Use of TDM and Need for TDM, Methods of TDM or Estimation of TDM-

Therapeutic drug monitoring (TDM) is the application of pharmacology, pharmacokinetic consultation, pathology and clinical medicine in the interpretation of measured drug concentration in body fluid.
TDM refers to the measurement of drug concentration in a biological fluid with the purpose of optimizing a patient’s drug therapy.
The aim of therapeutic drug monitoring-
The aim of TDM is optimizing drug therapy by knowing the measured concentration and therapeutic effect and using this information is the case of the patient.
It’s used for measuring the drug concentration in body fluid including:
Suspect toxicity due to drug metabolite.A sub-therapeutic response to drug therapy.Assessment of drug therapy where the patient is clinically unstable.Assessment of potential drug interaction.Evaluation of patient compliance.
Use of TDM- Mostly TDM used in two situations- 1.For minimizing the risk of serious drug toxicity and assessment of the appropriateness of dosing for the drug used a…

Introduction of pharmacology (pharmacokinetics and pharmacodynamics), Pharmacotherapeutics, Clinical pharmacology, Chemotherapy and Toxicology –

Father of pharmacology- Oswald Schmiedeberg
Pharmacology word is derived from The Greek word Pharmacon - means drug and Logos means discourse.
Pharmacology is a science of drug it deals with a interaction of exogenously administered chemical molecules with living systems. Pharmacology is the platform that gives all knowledge about medicines and also gives the knowledge about how to medicine or drug affect our body and how to use medicine.
We can also study about the mechanism of action of drug and use of all medicines.
Pharmacology is an experimental science was ushered by Rudolf Buchheim who founded the first institute of pharmacology in 1847 in German. In the later part of 19th century Oswald Schmiedeberg regarded as the Father of pharmacology .
What is drug-
French word- Drougue means Dry herb. It is a single active chemical that is present in medicine  and used for a diagnosis, prevention, treatment/cure of disease.
WHO definition of Drug- Drug is any substance or product …


When blood from one person transfer to another person then donors blood should be matches with acceptor blood otherwise there is mismatching between to cause death.
In RBC membrane several class of antigen are present in which two most important types are—
1.ABO system
2.Rh factor
In ABO system cell membrane of RBC contain antigen called Agglutinogen. There are two type of Agglutinogen present in human blood A and B. S divided into  4 groups-

Blood group ABlood group B  Blood group ABBlood group O
Blood group A- Person whose RBC membrane contains A agglutinogen.
Blood group B- Person whose RBC membrane contains B agglutinogen.
Blood group AB-  Person whose RBC membrane contains A and B  both agglutinogen.
Blood group O- Person whose RBC membrane contains  no agglutinogen.
Antibodies (Agglutinins) of ABO group-
Antibodies present in plasma. It divided into two sub classes-
Anti AAnti B Blood group A- plasma contain Anti B antibody.
Blood group B- plasma contain Anti A antibody